Dipl.-Ing. Christoph Bauer, PhD BSc BA

Post-Doc - Zentrum für Regenerative Medizin

Projekte (Auszug Forschungs­datenbank)

Laufende Projekte

3D-printed ceramic-based partial Implants for knee hemiarthroplasty

Projektzeitraum: 01.04.2022–31.03.2025
Projektverantwortung (Universität für Weiterbildung Krems): Christoph Bauer
Fördergeber: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

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3D-gedruckte Hydrogele und injizierbare Hydrogele in einem ex vivo-Knorpeldefektmodell

Projektzeitraum: 01.04.2021–31.12.2023
Projektverantwortung (Universität für Weiterbildung Krems): Christoph Bauer
Fördergeber: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

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Abgeschlossene Projekte

Treatment of OA using glucocorticoids and hyaluronic acid

Projektzeitraum: 01.09.2019–31.08.2021
Projektverantwortung (Universität für Weiterbildung Krems): Stefan Nehrer
Fördergeber: Unternehmen

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Lifetime assessment and prediction of partial replacement technology

Projektzeitraum: 01.01.2017–30.06.2020
Projektverantwortung (Universität für Weiterbildung Krems): Christoph Stotter
Fördergeber: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Förderprogramm: Life Science Call NFB

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Etablierung eines in vitro Arthrose-Modells

Projektzeitraum: 01.01.2016–30.06.2019
Projektverantwortung (Universität für Weiterbildung Krems): Christoph Bauer
Fördergeber: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Förderprogramm: Life Science Call NFB

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Evaluierung von anti-inflammatorischen und chondroprotektiven Effekten von Viskosupplementika aus unmodifizierter sowie thiolisierter Hyaluronäure

Projektzeitraum: 02.07.2012–30.06.2015
Projektverantwortung (Universität für Weiterbildung Krems): Stefan Nehrer
Fördergeber: FFG
Förderprogramm: FFG (Bridge)

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Surface structuring/modification concepts for tribological applications Tribo-modelling of bio-medical friction systems

Projektzeitraum: 01.10.2010–31.03.2015
Projektverantwortung (Universität für Weiterbildung Krems): Stefan Nehrer
Fördergeber: FFG
Förderprogramm: COMET

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Entwicklung von Transplantaten aus modifizierter Hyaluronsäure für die Behandlung von Knorpeldefekten

Projektzeitraum: 01.05.2009–31.12.2012
Projektverantwortung (Universität für Weiterbildung Krems): Stefan Nehrer
Fördergeber: FFG
Förderprogramm: FFG (Bridge)

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Publikationen (Auszug Forschungs­datenbank)

Kühnel, H.; Pasztorek, M.; Kuten-Pella, O.; Kramer, K.; Bauer, C.; Lacza, L.; Nehrer, S. (2024). Effects of Blood-Derived Products on Cellular Senescence and Inflammatory Re-sponse: A Study on Skin Rejuvenation. Curr. Issues Mol. Biol., Volume 46/ Issue 3: 1865–1885

Bauer, C.; Moser, L.B.; Kern, D.; Jeyakumar, V.; Nehrer, S. (2023). The Combination of Glucocorticoids and Hyaluronic Acid Enhances Efficacy in IL-1ß/IL-17-Treated Bovine Osteochondral Grafts Compared with Individual Application. International Journal of Molecular Sciences, 24: https://doi.org/10.3390/ijms241814338

Moser, L.B.; Bauer, C.; Otahal, A.; Kern, D.; Dammerer, D.; Zantop, T.; Nehrer, S. (2023). Mincing bovine articular cartilage with commercially available shavers reduces the via-bility of chondrocytes compared to scalpel mincing. J Exp Orthop., 10(1): doi: 10.1186/s40634-023-00661-5.

Bauer, C.; Moser, L.B.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2022). Increased Chondroprotective Effect of Combining Hyaluronic Acid with a Glucocorticoid Compared to Separate Administration on Cytokine-Treated Osteoarthritic Chondrocytes in a 2D Culture. Biomedicines, 10: doi:10.3390/biomedicines10071733

Pilecky, M.; Harm, S.; Bauer, C.; Zottl, J.; Emprechtinger, R.; Eichhorn, T.; Schildböck, C.; Ecker, M.; Willheim, M.; Weber, V.; Hartmann, J. (2022). Performance of lateral flow assays for SARS-CoV-2 compared to RT-qPCR. J Infect, Jan 14: S0163-4453(22)00011-1

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Klestil, T.; Franek, F.; Nehrer, S. (2021). Biotribological Tests of Osteochondral Grafts after Treatment with Pro-Inflammatory Cytokines. Cartilage, Epub ahead of print: 10.1177/1947603521994900

Jeyakumar, V.; Amraish, N.; Niculescu-Morzsa, E.; Bauer, C.; Pahr, D.; Nehrer, S. (2021). Decellularized Cartilage Extracellular Matrix Incorporated Silk Fibroin Hybrid Scaffolds for Endochondral Ossification Mediated Bone Regeneration. International Journal of Molecular Sciences, 22(8): doi.org/10.3390/ijms22084055

Moser, L; Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Nehrer, S. (2021). Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro. International Journal of Molecular Sciences, 22: 10.3390/ijms222111503

Stotter, C.; Bauer, C.; Simlinger, B.; Ripoll, MR.; Franek, F.; Klestil, T.; Nehrer, S. (2020). Biotribological testing and analysis of articular cartilage sliding against metal for implants. Journal of Visualized Experiments, Issue 159: ka

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Tóth, I.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Effect of osteochondral graft orientation in a biotribological test system. Journal of Orthopaedic Research, Mar, 37(3): 10.1002/jor.24236

Bauer, C.; Stotter, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Simlinger, B.; Rodriguez Ripoll, M.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Concentration-Dependent Effects of Cobalt and Chromium Ions on Osteoarthritic Chondrocytes. Cartilage, Epub ahead of print: 10.1177/1947603519889389

Göcerler, H.; Pfeil, B.; Franek, F.; Bauer, C.; Niculescu-Morzsa, E.; Nehrer, S. (2019). The dominance of water on lubrication properties of articular joints. Industrial Lubrication and Tribology, Epub ahead of print: 10.1108/ILT-02-2019-0064

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2019). Redifferentiation of Articular Chondrocytes by Hyperacute Serum and Platelet Rich Plasma in Collagen Type I Hydrogels. International Journal of Molecular Sciences, Jan 14;20(2): 10.3390/ijms20020316

Stojanovic, B.; Bauer, C.; Stotter, C.; Klestil, T.; Nehrer, S.; Franek, F.; Rodriguez Ripoll, M. (2019). Tribocorrosion of a CoCrMo alloy sliding against articular cartilage and impact of metal ion release on chondrocytes. Acta biomaterialia, Volume 94: 597-609

Stotter, C.; Stojanovic, B.; Bauer, C.; Rodriguez Ripoll, M.; Franek, F.; Klestil, T.; Nehrer, S. (2019). Effects of Loading Conditions on Articular Cartilage in a Metal-on-Cartilage Pairing. Journal of Orthopaedic Research, Epub ahead of print: 10.1002/jor.24426

Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2017). Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits-a pilot study. Journal of Experimental Orthopaedics, 4(1):14: 14

Bauer, C.; Niculescu-Morzsa, E.; Nehrer, S. (2017). A protocol for gene expression analysis of chondrocytes from bovine osteochondral plugs used for biotribological applications. MethodsX, 4: 423-428

Jeyakumar, V.; Halbwirth, F.; Niculescu-Morzsa, E.; Bauer, C.; Zwickl, H.; Kern, D.; Nehrer, S. (2017). Chondrogenic Gene Expression Differences between Chondrocytes from Osteoarthritic and Non-OA Trauma Joints in a 3D Collagen Type I Hydrogel. Cartilage, 8(2): 191-198

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2017). Platelet-Rich Plasma Supports Proliferation and Redifferentiation of Chondrocytes during In Vitro Expansion. Frontiers in Bioengineering and Biotechnology, 5:75: doi: 10.3389/fbioe.2017.00075

Bauer, C.; Berger, M.; Baumgartner, R.R.; Höller, S.; Zwickl, H.; Niculescu-Morzsa, E.; Halbwirth, F.; Nehrer, S. (2016). A Novel Cross-Linked Hyaluronic Acid Porous Scaffold for Cartilage Repair: An In Vitro Study With Osteoarthritic Chondrocytes. Cartilage, 7(3): 265–273

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Vorträge (Auszug Forschungs­datenbank)

Co-Administration of Glucocorticoid and Hyaluronic Acid in a 2D-culture with cytokine-treated osteoarthritic Chondrocytes

16th World Congress of the International Cartilage Regeneration & Joint Preservation Society (ICRS 2022), 13.04.2022

Biotribological tests of osteochondral grafts after treatment with pro-inflammatory cytokines

International Conference on Biotribology, 27.04.2021

Effect of orientation on osteochondral grafts in a biotribological test system

International Conference on BioTribology, Montreal, Canada, 27.09.2018

Blood compatibility of Antimicrobial Peptides

IMAP 2018, 8th International Meeting on Antimicrobial Peptides, Edinburgh, UK, 03.09.2018

Effect of orientation on osteochondral grafts in a biotribological test system

8th World Congress of Biomechanics, Dublin, Ireland, 07.07.2018

Effect of orientation on osteochondral grafts in a biotribological test system

ORS 2018 Annual Meeting, New Orleans, 12.03.2018

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo

ORS Orlando, 05.03.2016

Effect of high-molecular weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation system with M1 macrophages

32. Jahrestagung der Österreichischen Gesellschaft für Orthopädie und orthopädische Chirurgie, 31.10.2015

Effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation system with M1 macrophages

ÖGO Wien, 31.10.2015

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo.

World Conference on Regenerative Medicine, Leipzig, Germany, 21.10.2015

Effect of high-molecular weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation system with M1 macrophages.

World Conference on Regenerative Medicine, Leipzig, Germany, 21.10.2015

Effect of high-molecular weight hyaluronic acid on osteoarthritic chondrocytes in an in vitro co-cultivation system with M1 macrophges

4th TERMIS World Congress, Boston, USA, 08.09.2015

Effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation system with M1 macrophages

TERMIS Weltkongress Boston, 08.09.2015

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo

12th World Congress of the International Cartilage Repair Society (ICRS), Chicago, USA, 09.05.2015

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo

ICRS Chicago, 08.05.2015

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo

AGA Innsbruck 2014, 18.09.2014

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo

AGA Innsbruck, 18.09.2014

Cross-linked hyaluronic acid as a scaffold for the treatment of cartilage defects

ICRS Izmir, 14.09.2013

Characterization of cross-linked hyaluronic acid scaffolds in regard for the usage in cartilage regeneration

ÖGO Krems, 12.09.2013

Cross-linked hyaluronic acid as a scaffold for the treatment of cartilage defects

OARSI Philadelphia, 17.04.2013

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