Christoph Bauer

Dipl.-Ing. Christoph Bauer, PhD BSc BA

Post-Doc - Center for Regenerative Medicine

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Projects (Extract Research Database)

Running projects

3D-printed ceramic-based partial Implants for knee hemiarthroplasty

Duration: 01/04/2022–31/03/2025
Principle investigator for the project (University for Continuing Education Krems): Christoph Bauer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

3D-printed and injectable hydrogels in an ex vivo cartilage defect model

Duration: 01/04/2021–31/12/2023
Principle investigator for the project (University for Continuing Education Krems): Christoph Bauer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

Completed projects

Treatment of OA using glucocorticoids and hyaluronic acid

Duration: 01/09/2019–31/08/2021
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Unternehmen

Tribocorrosion

Duration: 01/01/2017–30/06/2020
Principle investigator for the project (University for Continuing Education Krems): Christoph Stotter
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB

Establishment of an in vitro osteoarthritis model

Duration: 01/01/2016–30/06/2019
Principle investigator for the project (University for Continuing Education Krems): Christoph Bauer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB

Evaluierung von anti-inflammatorischen und chondroprotektiven Effekten von Viskosupplementika aus unmodifizierter sowie thiolisierter Hyaluronäure

Duration: 02/07/2012–30/06/2015
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: FFG
Program: FFG (Bridge)

Surface structuring/modification concepts for tribological applications Tribo-modelling of bio-medical friction systems

Duration: 01/10/2010–31/03/2015
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: FFG
Program: COMET

Entwicklung von Transplantaten aus modifizierter Hyaluronsäure für die Behandlung von Knorpeldefekten

Duration: 01/05/2009–31/12/2012
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: FFG
Program: FFG (Bridge)

Publications (Extract Research Database)

Kühnel, H.; Pasztorek, M.; Kuten-Pella, O.; Kramer, K.; Bauer, C.; Lacza, L.; Nehrer, S. (2024). Effects of Blood-Derived Products on Cellular Senescence and Inflammatory Re-sponse: A Study on Skin Rejuvenation. Curr. Issues Mol. Biol., Volume 46/ Issue 3: 1865–1885

Bauer, C.; Moser, L.B.; Kern, D.; Jeyakumar, V.; Nehrer, S. (2023). The Combination of Glucocorticoids and Hyaluronic Acid Enhances Efficacy in IL-1ß/IL-17-Treated Bovine Osteochondral Grafts Compared with Individual Application. International Journal of Molecular Sciences, 24: https://doi.org/10.3390/ijms241814338

Moser, L.B.; Bauer, C.; Otahal, A.; Kern, D.; Dammerer, D.; Zantop, T.; Nehrer, S. (2023). Mincing bovine articular cartilage with commercially available shavers reduces the via-bility of chondrocytes compared to scalpel mincing. J Exp Orthop., 10(1): doi: 10.1186/s40634-023-00661-5.

Bauer, C.; Moser, L.B.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2022). Increased Chondroprotective Effect of Combining Hyaluronic Acid with a Glucocorticoid Compared to Separate Administration on Cytokine-Treated Osteoarthritic Chondrocytes in a 2D Culture. Biomedicines, 10: doi:10.3390/biomedicines10071733

Pilecky, M.; Harm, S.; Bauer, C.; Zottl, J.; Emprechtinger, R.; Eichhorn, T.; Schildböck, C.; Ecker, M.; Willheim, M.; Weber, V.; Hartmann, J. (2022). Performance of lateral flow assays for SARS-CoV-2 compared to RT-qPCR. J Infect, Jan 14: S0163-4453(22)00011-1

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Klestil, T.; Franek, F.; Nehrer, S. (2021). Biotribological Tests of Osteochondral Grafts after Treatment with Pro-Inflammatory Cytokines. Cartilage, Epub ahead of print: 10.1177/1947603521994900

Jeyakumar, V.; Amraish, N.; Niculescu-Morzsa, E.; Bauer, C.; Pahr, D.; Nehrer, S. (2021). Decellularized Cartilage Extracellular Matrix Incorporated Silk Fibroin Hybrid Scaffolds for Endochondral Ossification Mediated Bone Regeneration. International Journal of Molecular Sciences, 22(8): doi.org/10.3390/ijms22084055

Moser, L; Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Nehrer, S. (2021). Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro. International Journal of Molecular Sciences, 22: 10.3390/ijms222111503

Stotter, C.; Bauer, C.; Simlinger, B.; Ripoll, MR.; Franek, F.; Klestil, T.; Nehrer, S. (2020). Biotribological testing and analysis of articular cartilage sliding against metal for implants. Journal of Visualized Experiments, Issue 159: ka

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Tóth, I.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Effect of osteochondral graft orientation in a biotribological test system. Journal of Orthopaedic Research, Mar, 37(3): 10.1002/jor.24236

Bauer, C.; Stotter, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Simlinger, B.; Rodriguez Ripoll, M.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Concentration-Dependent Effects of Cobalt and Chromium Ions on Osteoarthritic Chondrocytes. Cartilage, Epub ahead of print: 10.1177/1947603519889389

Göcerler, H.; Pfeil, B.; Franek, F.; Bauer, C.; Niculescu-Morzsa, E.; Nehrer, S. (2019). The dominance of water on lubrication properties of articular joints. Industrial Lubrication and Tribology, Epub ahead of print: 10.1108/ILT-02-2019-0064

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2019). Redifferentiation of Articular Chondrocytes by Hyperacute Serum and Platelet Rich Plasma in Collagen Type I Hydrogels. International Journal of Molecular Sciences, Jan 14;20(2): 10.3390/ijms20020316

Stojanovic, B.; Bauer, C.; Stotter, C.; Klestil, T.; Nehrer, S.; Franek, F.; Rodriguez Ripoll, M. (2019). Tribocorrosion of a CoCrMo alloy sliding against articular cartilage and impact of metal ion release on chondrocytes. Acta biomaterialia, Volume 94: 597-609

Stotter, C.; Stojanovic, B.; Bauer, C.; Rodriguez Ripoll, M.; Franek, F.; Klestil, T.; Nehrer, S. (2019). Effects of Loading Conditions on Articular Cartilage in a Metal-on-Cartilage Pairing. Journal of Orthopaedic Research, Epub ahead of print: 10.1002/jor.24426

Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2017). Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits-a pilot study. Journal of Experimental Orthopaedics, 4(1):14: 14

Bauer, C.; Niculescu-Morzsa, E.; Nehrer, S. (2017). A protocol for gene expression analysis of chondrocytes from bovine osteochondral plugs used for biotribological applications. MethodsX, 4: 423-428

Jeyakumar, V.; Halbwirth, F.; Niculescu-Morzsa, E.; Bauer, C.; Zwickl, H.; Kern, D.; Nehrer, S. (2017). Chondrogenic Gene Expression Differences between Chondrocytes from Osteoarthritic and Non-OA Trauma Joints in a 3D Collagen Type I Hydrogel. Cartilage, 8(2): 191-198

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2017). Platelet-Rich Plasma Supports Proliferation and Redifferentiation of Chondrocytes during In Vitro Expansion. Frontiers in Bioengineering and Biotechnology, 5:75: doi: 10.3389/fbioe.2017.00075

Bauer, C.; Berger, M.; Baumgartner, R.R.; Höller, S.; Zwickl, H.; Niculescu-Morzsa, E.; Halbwirth, F.; Nehrer, S. (2016). A Novel Cross-Linked Hyaluronic Acid Porous Scaffold for Cartilage Repair: An In Vitro Study With Osteoarthritic Chondrocytes. Cartilage, 7(3): 265–273

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Lectures (Extract Research Database)

Co-Administration of Glucocorticoid and Hyaluronic Acid in a 2D-culture with cytokine-treated osteoarthritic Chondrocytes

16th World Congress of the International Cartilage Regeneration & Joint Preservation Society (ICRS 2022), 13/04/2022

Biotribological tests of osteochondral grafts after treatment with pro-inflammatory cytokines

International Conference on Biotribology, 27/04/2021

Effect of orientation on osteochondral grafts in a biotribological test system

International Conference on BioTribology, Montreal, Canada, 27/09/2018

Blood compatibility of Antimicrobial Peptides

IMAP 2018, 8th International Meeting on Antimicrobial Peptides, Edinburgh, UK, 03/09/2018

Effect of orientation on osteochondral grafts in a biotribological test system

8th World Congress of Biomechanics, Dublin, Ireland, 07/07/2018

Effect of orientation on osteochondral grafts in a biotribological test system

ORS 2018 Annual Meeting, New Orleans, 12/03/2018

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo

ORS Orlando, 05/03/2016

Effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation system with M1 macrophages

ÖGO Wien, 31/10/2015

Effect of high-molecular weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation system with M1 macrophages

32. Jahrestagung der Österreichischen Gesellschaft für Orthopädie und orthopädische Chirurgie, 31/10/2015

Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo.

World Conference on Regenerative Medicine, Leipzig, Germany, 21/10/2015

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