Assoz. Prof. Mag. Andrea De Luna, PhD
- andrea.de-luna@donau-uni.ac.at
- +43 2732 893-5504
- To contact form
- Campus Krems, Tract C, 3rd Floor, C 3.14
- University for Continuing Education Krems
- Center for Regenerative Medicine
- Dr.-Karl-Dorrek-Straße 30
- 3500 Krems
- Austria
Projects (Extract Research Database)
Running projects
Duration: 01/10/2024–31/03/2028
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: FWF
Duration: 01/06/2024–31/05/2027
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Completed projects
Extracellular vesicles from Hoffa´s fat pad- a new strategy for cartilage regeneration
Duration: 01/03/2020–28/02/2023
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB
The Role of microvesicles from blood derived products in osteoarthritis
Duration: 01/01/2018–29/02/2020
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Technologieförderung NÖ
Durchführbarkeitsstudie des Serumisolators hypACT
Duration: 02/05/2017–31/05/2017
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Unternehmen
Program: ---
Identification of novel treatment options for osteoarthritis
Duration: 05/11/2012–30/04/2016
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB
Publications (Extract Research Database)
Otahal, A.; Kramer, K.; Neubauer, M.; Gulová, S.; Lacza, Z.; Nehrer, S.; De Luna, A. (2024). Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production. Stem Cell Research and Therapy, 15: https://doi.org/10.1186/s13287-024-03681-9
Neubauer, M.; Otahal, A.; Kuten, S.; Sherman, S.L.; Moser, L.; Kramer K.; DeLuna, A.; Neugebauer, J.; Dammerer, D.; Muellner, T.; Nehrer, S. (2023). Infra-patellar fat pad-derived mesenchymal stem cells maintain their chondrogenic dif-ferentiation potential after arthroscopic harvest with blood-product supplementation. Int Orthop., 30: doi: 10.1007/s00264-023-05930-7
Otahal, A.; De Luna, A.; Mobasheri, A.; Nehrer, S. (2023). Extracellular Vesicle Isolation and Characterization for Applications in Cartilage Tissue Engineering and Osteoarthritis Therapy. In: Humana Press, Cartilage Tissue Engineering: 123-140, Springer Protocols, United States of America
Otahal, A.; Tischer, T.; De Luna, A.; Nehrer, S. (2023). Plättchenreiches Plasma und andere Blutprodukte – neue Forschungsaspekte zur Wirkung von Blutderivaten und klinische Ergebnisse bei Gonarthrose. Knie Journal, 5(3): 142–149, Springer
Kuten-Pella, O.; De Luna, A.; Kramer, K.; Neubauer, M.; Nehrer, S.; Lacza, Z. (2021). Regenerative Potential of Blood-Derived Products in 3D Osteoarthritic Chondrocyte Culture System. Curr Issues Mol Biol, 43(2): 665-675
Olmos Calvo, I.; Kuten-Pella, O.; Kramer, K.; Madár, À.; Takács, S.; Kardos, D.; Simon, D.; Erdö-Bonyár, S.; Berki, T.; De Luna, A.; Nehrer, S.; Lacza Z. (2021). Optimization of Lyophilized Hyperacute Serum (HAS) as a Regenerative Therapeutic in Osteoarthritis. Int J Mol Sci, 22 (14): 7496
Otahal, A.; Kramer, K.; Kuten-Pella, O.; Moser, L.; Neubauer, M.; Lacza,Z.; Nehrer, S.; De Luna, A. (2021). Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation Model. Int J Mol Sci., 22(13): 7224
Otahal, A.; Kuten-Pella, O.; Kramer, K.; Neubauer, M.; Lacza, Z.; Nehrer, S.; De Luna, A. (2021). Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products. Sci Rep., 12;11(1): 5823
De Luna, A.; Otahal, A.; Nehrer, S. (2020). Mesenchymal Stromal Cell-Derived Extracellular Vesicles - Silver Linings for Cartilage Regeneration? Frontiers in Cell and Developmental Biology, 8:593386: 10.3389/fcell.2020.593386
Otahal, A.; Kramer, K.; Kuten-Pella, O.; Weiss, R.; Stotter, C.; Lacza, Z.; Weber, V.; Nehrer, S.; De Luna, A. (2020). Characterization and chondroprotective effects of extracellular vesicles from plasma- and serum-based autologous blood-derived products for osteoarthritis therapy. Front Bioeng Biotechnol, Sep 25: 584050
Kuten, O.; Simon, M.; Hornyák, I.; De Luna-Preitschopf, A.; Nehrer, S.; Lacza, Z. (2018). The Effects of Hyperacute Serum on Adipogenesis and Cell Proliferation of Mesenchymal Stromal Cells. Tissue Engineering Part A, Vol. 24, No. 11-12: doi: 10.1089/ten.TEA.2017.0384
De Luna-Preitschopf, A.; Zwickl, H.; Nehrer, S.; Hengstschläger, M.; Mikula, M. (2017). Rapamycin Maintains the Chondrocytic Phenotype and Interferes with Inflammatory Cytokine Induced Processes. International Journal of Molecular Sciences, 18(7): doi:10.3390/ijms18071494
Preitschopf, A.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Zwickl, H.; Rosner, M.; Joó, J.G.; Nehrer, S; Hengstschläger, M; Mikula, M. (2016). Rapamycin-Induced Hypoxia Inducible Factor 2A Is Essential for Chondrogenic Differentiation of Amniotic Fluid Stem Cells. Stem Cells Translational Medicine: 580-90
Schörghofer, D.; Kinslechner, K.; Preitschopf, A.; Schütz, B.; Röhrl, C.; Hengstschläger, M.; Stangl, H.; Mikula, M. (2015). The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence . Reprod Biol Endocrinol, Vol. 13, No. 88
Üstün, S.; Lassnig, C.; Preitschopf, A.; Mikula, M.; Müller, M.; Hengstschläger, M.; Weichhart, T. (2015). Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models. Transplantation Immunology: 45-50
Üstün, S.; Lassnig, C.; Preitschopf, A.; Mikula, M.; Müller, M.; Hengstschläger, M.; Weichhart, T. (2015). Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models. Transpl Immunol.
Preitschopf, A.; Zwickl, H.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Rosner, M.; Joo, G.J.; Hengstschläger, M.; Nehrer, S.; Mikula, M. (2015). Rapamycin enhances Sox9 Expression during Chondrogenic Differentiation of Amniotic Fluid Stem Cells. Tissue Engineering Part A, September 2015, Volume 21, Supplement 1: 192
Preitschopf, A.; Zwickl, H.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Rosner, M.; Joó, J.; Hengstschläger, M.; Nehrer, S.; Mikula, M. (2015). Rapamycin enhances SOX9 expression during chondrogenic differentiation of amniotic fluid stem cells. Tissue Engineering Part A: 192-93
Preitschopf, A.; Li, K.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Thi Thanh Pham, H.; Rosner, M.; Joo, G.; Röhrl, C.; Weichhart, T.; Stangl, H.; Lubec, G.; Hengstschläger, M.; Mikula, M. (2014). mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression. Plos One
Preitschopf, A.; Busch, J.; Zwickl, H.; Nehrer, S.; Hengstschläger, M.; Mikula, M. (2014). Amniotic Fluid Stem Cells for the Treatment of Articular Cartilage Defects. In: Perinatal Stem Cells: 87-98, Springer Verlag
Lectures (Extract Research Database)
Extracellular vesicles from Hoffa Fat Pad derived MSC - silver linings for cartilage repair?
Jahrestagung des Vienna Center for Engineering in Medicine, 13/12/2023
Extracellular vesicles from Hoffa Fat Pad derived mesenchymal stem cells – friends or foe?
Webinar of the Italian Society of Stem Cells, 04/07/2023
Extracellular vesicles from Hoffa Fat Pad MSCs favor the osteoarthritic phenotype of chondrocytes
Annual Meeting of the Austrian Cluster of Tissue Regeneration, 03/05/2023
Extracellular vesicles in blood derived products
ICRS World Congress, 12/04/2023
Isolation and culture of Hoffa-derived adipose MSCs for extracellular vesicle production in a vertical wheel bioreactorÖGMBT W
ÖGMBT Workshop „Advanced Cell Culture Technologies", 17/03/2023
Extracellular vesicles from blood derived products for cartilage repair
ASEV/GSEV Joint Meeting, 28/10/2022
Extracellular Vesicles in Blood-Derived Products for Cartilage Repair? - a status report
Annual Meeting of the Austrian Cluster of Tissue Regeneration, 27/04/2022
Extracellular Vesicles in Blood-Derived Products for Cartilage Repair
ICRS World Congress, 14/04/2022
Effects of extracellular vesicles from blood derivatives on osteoarthritic chondrocytes
ASEV/GSEV Joint Meeting, Freising, Deutschland, 28/11/2019
Anti-coagulation influences properties of extracellular vesicles isolated from autologous blood derived products used for cartilage repair
World Congress of the International cartilage repair and joint preservation society, Vancouver, Kanada, 08/10/2019