Projects (Extract Research Database)

Running projects

Systematic literature review to identify effective preventive methods for bloodstream infections (BSI) and other infections, associated with peripheral intravascular catheters (PIVC)

Duration: 01/03/2023–20/10/2023
Principle investigator for the project (University for Continuing Education Krems): Andreea Dobrescu
Funding: andere internationale Organisationen

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Pharmacological Treatment of Acute Episodic Migraine Attacks

Duration: 15/02/2023–31/12/2024
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: Sonstige

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Developing rapid review guidance for clinical research

Duration: 01/02/2022–30/06/2024
Principle investigator for the project (University for Continuing Education Krems): Ursula Griebler
Funding: andere internationale Organisationen

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Completed projects

Primary Treatment of Confirmed SARS-CoV-2 Infection in Outpatient Settings: Surveillance Searches for Living Guidelines

Duration: 01/07/2022–30/06/2023
Principle investigator for the project (University for Continuing Education Krems): Isolde Sommer
Funding: andere internationale Organisationen

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Nonpharmacological versus Pharmacological Treatments for Major Depressive Disorder: Surveillance Searches for Living Guidelines

Duration: 01/07/2022–30/06/2023
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: andere internationale Organisationen

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WO24-Targeted Immune Modulators - Ulcerative Colitis and Crohn Diseases: Systematic Review Update

Duration: 01/07/2022–30/04/2023
Principle investigator for the project (University for Continuing Education Krems): Andreea Dobrescu
Funding: andere internationale Organisationen

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Use of preprint articles in prevention research – a mixed-methods approach

Duration: 01/10/2020–28/02/2023
Principle investigator for the project (University for Continuing Education Krems): Isolde Sommer

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The Austrian school health system: a status quo assessment

Duration: 01/07/2021–31/12/2022
Principle investigator for the project (University for Continuing Education Krems): Ursula Griebler
Funding: Bund (Ministerien)

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Pharmacological Versus Non-Pharmacological Interventions for the Treatment of Major Depressive Disorder

Duration: 10/06/2020–31/03/2022
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: andere internationale Organisationen

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HT19-04: Depressionen bei Kindern und Jugendlichen: Führt Psychotherapie im Vergleich zu anderen Therapien zu besseren Ergebnissen?

Duration: 01/12/2019–31/08/2021
Principle investigator for the project (University for Continuing Education Krems): Barbara Nußbaumer-Streit
Funding: andere internationale Organisationen

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Systematischer Review Point of Care Ultrasound

Duration: 11/10/2018–31/03/2021
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: andere internationale Organisationen

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Cochrane Review Update - Prävention häuslicher Bleibelastung bei Kindern

Duration: 13/03/2020–31/08/2020
Principle investigator for the project (University for Continuing Education Krems): Barbara Nußbaumer-Streit
Funding: andere internationale Organisationen

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Publications (Extract Research Database)

Dobrescu, A.I.; Persad, E.; Klerings, I.; Gartlehner, G. (2024). Update Alert: Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians. Ann Intern Med, onine ahead of print: 10.7326/L23-0441.

Affengruber, L.; Wagner, G.; Dobrescu, A.; Toromanova, A.; Chapman, A.; Persad, E.; Klerings, I.; Gartlehner, G. (2023). Values and Preferences of Patients With Depressive Disorders Regarding Pharmacologic and Nonpharmacologic Treatments. A Rapid Review. Annals of Internal Medicine, 176(2): 217-223.

Dobrescu, A.; Chapman, A.; Affengruber, L.; Persad, E.; Toromanova, A.; Wagner, G.; Klerings, I.; Emprechtinger, R.; Gartlehner, G. (2023). Cost-Effectiveness of First- and Second-Step Treatment Strategies for Major Depressive Disorder. A Rapid Review. Annals of Internal Medicine, 176(2): 212-216

Gartlehner, G.; Dobrescu, A.; Chapman, A.; Toromanova, A.; Emprechtinger, R.; Persad, E.; Affengruber, L.; Pieh, C.; Klerings, I.; Wagner, G. (2023). Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder. A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians. Annals of Internal Medicine, 176: 196-211

Griebler, U.; Dobrescu, A.; Ledinger, D.; Klingenstein, P.; Sommer, I.; Emprechtinger, R.; Persad, E.; Gadinger, A.; Trivella, M.; Klerings, I.; Nussbaumer-Streit, B. (2023). Evaluation of the interim Cochrane rapid review methods guidance—A mixed-methods study on the understanding of and adherence to the guidance. Research Synthesis Methods, https://doi.org/10.1002/jrsm.1656: 1-12

Sommer, I.; Dobrescu, A.; Ledinger, D.; Moser, I.; Thaler, K.; Persad, E.; Fangmeyer, M.; Emprechtinger, R.; Klerings, I.; Gartlehner, G. (2023). Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Review for the American College of Physicians. Annals of Internal Medicine, 176: 92-104

Sommer, I.; Ledinger, D.; Thaler, K.; Dobrescu, A.; Persad, E.; Fangmeyer, M.; Klerings, I.; Gartlehner, G. (2023). Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2). Annals of Internal Medicine, -: 1-10

Sommer, I.; Sunder-Plassmann, V.; Ratajczak, P.; Emprechtinger, R.; Dobrescu, A.; Griebler, U.; Gartlehner, G. (2023). Full publication of preprint articles in prevention research: an analysis of publication proportions and results consistency. Scientific Reports, 13:17034: https://doi.org/10.1038/s41598-023-44291-4

Affengruber, L.; Dobrescu, A.; Persad, E.; Klerings, I.; Wagner, G.; Sommer, I.; Gartlehner, G. (2022). Characteristics and recovery methods of studies falsely excluded during literature screening-a systematic review. Systematic Reviews, 11: 236

Dobrescu, A.I.; Ebenberger, A.; Harlfinger, J.; Griebler, U.; Klerings, I.; Nussbaumer-Streit, B.; Chapman, A.; Affengruber, L.; Gartlehner, G. (2022). Effectiveness of interventions for the remediation of lead-contaminated soil to prevent or reduce lead exposure - A systematic review. Science of The Total Environment, Volume 806, Part 1: https://doi.org/10.1016/j.scitotenv.2021.150480

Gartlehner, G.; Emprechtinger, R.; Hackl, M.; Jutz, F.L.; Gartlehner, J.E.; Nonninger, J.N.; Klerings, I.; Dobrescu, A.I. (2022). Assessing the magnitude of reporting bias in trials of homeopathy: a cross-sectional study and meta-analysis. BMJ Evidence-Based Medicine, Published Online First: 15 March 2022.: doi: 10.1136/bmjebm-2021-111846

Sommer, I.; Dobrescu, A.; Ledinger, D.; Moser, I.; Thaler, K.; Persad, E.; Fangmeyer, M.; Emprechtinger, R.; Klerings, I.; Gartlehner, G. (2022). Outpatient Treatment of Confirmed COVID-19. A Living, Rapid Review for the American College of Physicians. Annals of Internal Medicine, Online ahead of print.: 1-14

Sommer, I.; Harlfinger, J.; Kien, C.; Klerings, I.; Affengruber, L.; Dobrescu, A.; Griebler, U. (2022). Stakeholders’ perceptions and experiences of factors influencing the commissioning, delivery, and uptake of general health checks: a qualitative evidence synthesis (Protocol). Cochrane Database of Systematic Reviews, Issue 3: Art. No.: CD014796.

Dobrescu, A.; Gartlehner, G.; Wagner, G.; Chapman, A.; Moick, S.; Kahwati, L. (2022). Targeted immune modulators for rheumatoid arthritis and ankylosing spondylitis: update. Center for Evidence-based Policy, Oregon Health & Science University, -: -

Nußbaumer-Streit, B.; Kien, C.; Titscher, V.; Dobrescu, A.; Teufer, B.; Probst, T.; Strohmaier, C.; Stanak, M.; Zechmeister-Koss, I.; Kallab, S. (2022). Depression bei Kindern und Jugendlichen. Führt Psychotherapie im Vergleich zu anderen Therapien zu besseren Ergebnissen? IQWiG-Bericht, Version 1.0: HTA-Nummer HT19-04

Dobrescu, A.; Nussbaumer-Streit, B.; Klerings, I.; Wagner, G.; Persad, E.; Sommer, I.; Herkner, H.; Gartlehner, G. (2021). Restricting evidence syntheses of interventions to English-language publications is a viable methodological shortcut for most medical topics: a systematic review. Journal of Clinical Epidemiology, 137: 209-217

Ewald, H., Klerings, I.; Wagner, G.; Heise, T.L.; Dobrescu, A.I.; Armijo-Olivo, S.; Stratil, J.M.; Lhachimi, S.K.; Mittermayr, T.; Gartlehner, G.; Nussbaumer-Streit, B.; Hemkens, L.G. (2020). Abbreviated and comprehensive literature searches led to identical or very similar effect estimates: a meta-epidemiological study. Journal of Clinical Epidemiology, 128: 1-12

Nussbaumer-Streit, B.; Klerings, I.; Dobrescu, A.I.; Persad, E.; Stevens, A.; Garritty, C.; Kamel, C.; Affengruber, L.; King, V.J.; Gartlehner, G. (2020). Excluding non-English publications from evidence-syntheses did not change conclusions: a meta-epidemiological study. Journal of Clinical Epidemiology, 118: 42-54

Nussbaumer-Streit, B.; Mayr, V.; Dobrescu, A.I.; Chapman, A.; Persad, E.; Klerings, I.; Wagner, G.; Siebert, U.; Christof, C.; Zachariah, C.; Gartlehner, G.; (2020). Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review. Cochrane Database of Systematic Reviews, Issue 4: Art. No.: CD013574.

Nussbaumer-Streit, B.; Mayr, V.; Dobrescu; A.I.; Wagner, G.; Chapman, A.; Pfadenhauer, L.M.; Lohner, S.; Lhachimi, S.K.; Busert, L.K.; Gartlehner, G.; (2020). Household interventions for secondary prevention of domestic lead exposure in children (Review). Cochrane Database of Systematic Reviews, Issue 10: Art. No.: CD006047

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Lectures (Extract Research Database)

Stakeholders' perceptions of factors influencing uptake, delivery, and commissioning of health checks

16. European Public Health Conference, 11/11/2023

Workshop on Guideline Development using GRADE

WHO, 12/10/2023

Workshop on Guideline Development using GRADE

WHO, 11/10/2023

Effectiveness of interventions for the remediation of lead-contaminated soil to prevent or reduce lead exposure

Nachhaltigkeitstag der Universität für Weiterbildung Krems, Best Paper Award, 05/10/2023

Breaking Ground or Breaking Bad? Examining the Fate of Preprints in Prevention Research with a Mixed Methods Study

Cochrane Colloquium, 04/09/2023

Rating the Certainty of Evidence. Workshop on Cost Conscious Care.

European Association of Neurology, 30/06/2023

Evidence-based medicine - new field or already well-known?

SMART Diaspora Workshop, 12/04/2023

Targeted Immune Modulators for Ulcerative Colitis and Crohn’s Disease

DERP Governance Call, 06/04/2023

Prädiktoren von falsch ausgeschlossenen Studien bei der Literaturdurchsicht von systematischen Reviews: ein systematischer Review und eine Methodenstudie

22. Jahrestagung EbM-Kongress 2021, 25/02/2021

Increased risks of false-positive or false-negative findings are common in outcomes graded as high certainty of evidence

25th Cochrane Colloquium Edinburgh, Großbritannien, 18/09/2018

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